This book provides a comprehensive introduction to biostatistics and its integration with computer applications in biological research. It covers fundamental statistical concepts such as probability, sampling, hypothesis testing, and data analysis. The text explores the use of computer tools and software for managing, analyzing, and interpreting biological data. It also discusses applications in medical research, epidemiology, and environmental studies. Emphasis is placed on data-driven decision-making and the accurate interpretation of results. Practical examples and exercises help reinforce statistical concepts and computational techniques. By combining statistical theory with modern computing tools, the book serves as a valuable resource for students and professionals in life sciences and research.